Stat3 (磷酸化-Ser727)多克隆抗體
| 貨號(hào) | 品牌 | CAS | 規(guī)格 | 銷售價(jià)(RMB) | 折扣價(jià)(RMB) | 備注 | 數(shù)量 |
| ABP0046-100μL | Abbkine | 無 | 100μL | 1998 | 1998 | 無 |
商品信息
| 產(chǎn)品英文名稱 | Stat3 (phospho Ser727) Polyclonal Antibody |
| 免疫原 | 合成多肽：人源Stat3 磷酸化位點(diǎn)為中心：S727 |
| 宿主 | 兔 |
| 反應(yīng)性 | 人, 大鼠, 小鼠, 猴 |
| 應(yīng)用 | ELISA, IF, IHC-P, IP, WB |
| 實(shí)驗(yàn)建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:500-1:2000，IF：1:50-1:200，IHC-P：1:100-1:300，IP：2-5 ug/mg lysate，ELISA：1:10000。 |
| 克隆性 | 多克隆 |
| 純化工藝 | 使用表位特異性的免疫原，通過親和層析，從兔抗血清中親和純化抗體。 |
商品屬性
| 產(chǎn)品形式 | 液體溶液 |
| 濃度 | 1 mg/ml |
| 分子量 | 85 KD |
| 儲(chǔ)存緩沖液 | PBS緩沖液（pH 7.4），含有0.5%BSA（穩(wěn)定劑），0.02％疊氮化鈉（防腐劑）和50％甘油。 |
| 保存建議 | 自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。 |
| 運(yùn)輸條件 | 藍(lán)冰運(yùn)輸 |
| 警告 | 本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。 |
附加信息
| 背景 | Signal transducer and activator of transcription 3 encoded by STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Signal transducer and activator of transcription 3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. Signal transducer and activator of transcription 3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in STAT3 are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| 基因ID | 6774 |
| 別名 | STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor |
| 其它 | 該抗體可檢測(cè)內(nèi)源蛋白 |
| 蛋白質(zhì)ID | P40763 |
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